摘要
目的:观察瑞芬太尼联合异丙酚在纤维支气管镜检查的临床应用。方法:抽取进行纤维支气管镜检查的患者80例,随机分为两组,试验组(瑞芬太尼+异丙酚)和对照组(利多卡因),每组40例。试验组(RP组)给予静脉注射异丙酚1mg/kg持续60s,随后用瑞芬太尼微泵以0.1μg/(kg·min)持续输注,待患者入睡、呼之不应、睫毛反射消失后,开始纤维支气管镜检查;对照组(L组)给予2%利多卡因10ml表面麻醉。结果:试验组麻醉起效快,血流动力学稳定,组内检查前中后比较变化不大(P>0.05),对照组入镜后血压、心率较检查前明显升高,呼吸频率增快(P<0.05),对照组呛咳和躁动不安发生率明显高于试验组(P<0.01),患者满意度低于试验组(P<0.01)。两组患者在供氧状态下SpO2均≥98%。结论:瑞芬太尼联合异丙酚用于纤维支气管镜检查安全舒适,可控性好,值得临床推广。
Objective： To evaluate the clinical application of remifentanil combing with propofol to fiberoptic bronchoscopy examination. Methods： 80 patients undergoing check of fiberoptic bronchoscope were randomly divided into 2 groups with 40 patients in each. Group RP was given remifentanil and propofol, group L only received topical anesthesia of lidocaine（2%）.Hemodynamic date （MAP, HR, RR and SpO2） were recorded.0bserve adverse effects and satisfaction of patient.Results： Group RP took effect very quickly.The MAP and HR was more stable in the group RP.The bucking and the agitation of group RP were lower than that in group L（P〈0.01）.Patient＇s satisfaction of group RP was higher than the other（P〈0.01）.The SpO2 were more than 98% with the oxgen supporting in every group. Conclusion： It was safe and effective using remifentanil combing with propofol to fiberoptie bronehoseopy examination. It had the advantages of good control, less hemodynamie effect and can be used clinically.
出处
《中外医学研究》
2013年第2期3-5,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
基金
阳江市科研项目(项目编号:卫[2011]51)
关键词
纤维支气管镜
瑞芬太尼
异丙酚
Fiberoptic bronchoscopy examination
Remifentanil
Propofol
