摘要
目的探讨长期600mg/d的厄贝沙坦和针对导致慢性肾功能衰竭的多因素治疗联合使用对于糖尿病肾病患者的疗效。方法研究对象为2007年5月至2011年5月在我院确诊为76例确诊为糖尿病肾病的患者,测量治疗前后的血压,血钾,HbA1c,尿钠,尿素,LDL,三酰甘油,HDL,血肌酐和尿蛋白。结果治疗前后的药物种类的变化没有统计学意义,血压,尿钠,LDL,尿素,血肌酐和尿蛋白的变化均有统计学意义(P<0.05),HbA1c,血钾,血红蛋白和HDL的变化没有统计学意义。结论 600mg/d的厄贝沙坦联合针对导致慢性肾功能衰竭多因素的治疗对于糖尿病肾病的治疗是有效地,也是安全的,能够有效地减少尿蛋白的排除和保护肾功能。
Objective To investigate the long-term 600mg/day of irbesartan and the efficacy of the treatment of joint use of multifactors that lead to chronic renal failure in patients with diabetic nephropathy.Methods The subjects for May 2007-2011 in May in our hospital diagnosed 76 cases diagnosed as diabetic nephropathy patients before and after treatment,the measurement of blood pressure,serum potassium,HbA1c,urinary sodium,urea,LDL,triglycerides,HDL,serum creatinine and urine protein.Result No statistically significant changes in the types of drugs before and after treatment,blood pressure,urinary sodium,LDL,urea,creatinine and urinary protein changes were statistically significant（P 0.05）,HbA1c,serum potassium,hemoglobin,and HDL,The change is not statistically significant.Conclusion 600mg/day irbesartan joint for the result in the treatment of chronic renal failure multifactorial effective for the treatment of diabetic nephropathy,is safe,can be effective in reducing urinary protein exclusion and protection of renal function.
出处
《中国医药指南》
2012年第36期423-424,共2页
Guide of China Medicine
关键词
厄贝沙坦
糖尿病肾病
Irbesartan
Diabetic nephropathy
