摘要
目的比较简易精神状态量表(MMSE)与蒙特利尔认知评估量表(MoCA)在认知障碍早期阶段的筛查价值。方法采用MMSE与MoCA对93名非痴呆认知障碍患者与66名正常对照者进行认知功能评估,比较MMSE与MoCA对非痴呆认知障碍患者的筛查效果。结果非痴呆认知障碍组MMSE与MoCA评分均显著低于正常对照组。与MMSE相比,MoCA在非痴呆认知障碍筛查上具有较高的灵敏度、阴性预测值与约登指数,但特异度与阳性预测值较低。结论 MMSE与MoCA为临床住院患者认知障碍的有效筛查工具,两者联合使用可在临床工作中提高对非痴呆性认知障碍的诊断效力。
Objective to compare the screen value of mini-mental state examination（MMSE）and Montreal Cognitive Assessment（MoCA）in the early phase of cognitive disorder. Methods 93 non-dementia cognitive disorder patients and 66 normal controls were included in the current study. MMSE and MoCA were both utilized to investigate the cognitive function of subjects,the screen effect of which was further evaluated. Results the scores of MMSE and MoCA in non-dementia cognitive disorder group were both significantly lower relative to the normal control group. Compared to the MMSE, MoCA appeared remarkably superin sensitivity, negative predictive value and Youden Index,while showed inferiority（shortcomings？）in specificity and positive predictive value in the screen of non-dementia cognitive disorder. Conclusion MMSE and MoCA are both effective screen tools in cognitive disorder for hospitalized patients, which could evaluate the diagnostic efficiency in clinic when combined together.
出处
《成都医学院学报》
CAS
2012年第4期648-650,共3页
Journal of Chengdu Medical College
