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上皮间质转化与肿瘤干细胞 被引量:6

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摘要 肿瘤干细胞是肿瘤组织中具有干细胞样特征的一群细胞,具有自我更新能力,保持肿瘤形成能力(tumorigenicity),可分化产生构成肿瘤组织的各种细胞,是肿瘤发生、转移及复发的源泉。在肿瘤(本文中所提肿瘤指上皮细胞来源肿瘤)进展过程中,原发肿瘤内的部分细胞发生上皮间质转化(EMT),转化的上皮细胞获得间质细胞特征,有利于其发生转移。近来有学者发现,
出处 《中华病理学杂志》 CAS CSCD 北大核心 2013年第1期62-65,共4页 Chinese Journal of Pathology
基金 湖北省教育厅科研计划项目(B20122411)
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参考文献38

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同被引文献50

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