摘要
目的探讨在新生儿重症监护病房（NICU）床边进行早产儿视网膜病变（ROP）激光治疗的临床效果及围手术期安全性。方法回顾性分析2009年3月至2011年7月，在八一儿童医院NICU内采取机械通气下肌松剂麻醉后，床边进行激光治疗的103例ROP患儿的临床资料。结果103例严重ROP患儿共199只眼接受了激光治疗（随访最短5个月），其中I区病变39例76只眼（38．2％），II区病变64例123只眼（61．8％），有附加病变91例180只眼（90．5％），经治疗后191只眼病变消退，8只眼发展至局部视网膜脱离，总体治愈率96．0％，其中I区89．5％，1I区100％。103例患儿无一例出现术中风险，术后平均撤离呼吸机时间为（6．7±1．3）h。结论NICU床边进行严重ROP激光治疗是一种安全、有效的治疗模式，值得推广。
Objective To evaluate the efficacy and safety of the bedside diode laser photocoagulation for severe retinopathy of prematurity in neonatal intensive care unit （ NICU ）. Method Data of 103 patients with prethreshold or threshold retinopathy of prematurity （ ROP）, treated with diode laser photoablation after veeuronium-induced anesthesia and mechanical ventilation from March 2009 to July 2011 in NICU of Bayi Children＇s Hospital. Result Totally 199 eyes in 103 patients received laser therapy with at least 5 months follow up. Among these eyes, zone I disease was found in 76 eyes （ 38. 2% ） of 39 infants, zone ]I disease was found in 123 eyes （61.8%）of 64 infants and additional disease was found in 180 eyes of 91 infants. After treatment 191 （96. 0% ） of 199 eyes had favorable outcomes and 8 developed to partial retinal detachment. The rate of favorable outcomes in zone I diseases and zone 2 diseases were 89. 5% and 100% respectively. The laser therapy was undertaken in all patients safely and the use of ventilator was stopped quickly [ after a mean of （6.7 ± 1.3 ） h]. Conclusion Bedside laser photoeoagulation in NICU is a safe and effective treatment mode for severe ROP and should be used widely.
出处
《中华儿科杂志》
CAS
CSCD
北大核心
2013年第1期12-15,共4页
Chinese Journal of Pediatrics
关键词
早产儿视网膜病变
激光光凝术
新生儿重症监护
早产儿
治疗
Retinopathy of prematurity
Laser photocoagulation
Neonatal intensive care
Infant,premature
Therapy
