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胸腺因子D对鸡生长、免疫功能及血液中某些激素水平的影响 被引量:6

Effects of Thymic Factor D on Growth, Immunological Function and Blood Hormone Level in the Chicken
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摘要 80只 1日龄Avian鸡 ,随机分为实验组和对照组 ,每组 40只 自 1日龄开始 ,实验组鸡肌肉注射胸腺因子D(TFD) ,剂量 2mg/kg ,对照组注射生理盐水 ,隔日注射 ,共 5次 试验期 42d ,观察TFD对肉鸡生长、免疫及血液中某些激素水平的影响 结果表明 :1 )注射TFD可显著促进Avian鸡生长 2 ) 2 3日龄时实验组鸡的外周血T淋巴细胞百分率极显著高于对照组 (P <0 .0 1 ) 3)实验组在 2 8日龄时血浆甲状腺素 (T4 )水平显著高于对照组 (P <0 .0 5 ) ,三碘甲腺原氨酸 (T3 )、生长激素 (GH)水平均不同程度高于对照组 ,但差异不显著 (P >0 .0 5 ) Eighty day old chickens were randomly divided into two groups ( n =40). The treated group was injected via sternal muscle with thymic factor D at 3 mg/kg body weight every other day from day 1 to 10, while the control group was given the same volume of sterile 0.9% NaCl. All chickens were weighed once a week from day 14 on wards. Blood samples were collected and the concentrations of thyroxine (T 4). Trilodothyroxine (T 3) and growth hormone (GH) in the plasnas were measured by radioimmunoassay (RIA). The percentage of T cells were calculated on day and 23,38. The results showed that: 1) Injection with TFD promoted growth. 2) On day 23, the percentage of T cells between treated group and controe group was significantly different ( P <0.01). 3)The concentration of T 4 between the two groups was different ( P <0.05) on day 23. The concentrations of T 3 and GH of the treated group were higher than those of the control, but the difference was not significant ( P >0.05).
作者 傅伟龙 余斌
出处 《华南农业大学学报》 CAS CSCD 北大核心 2000年第2期68-71,共4页 Journal of South China Agricultural University
基金 广东省自然科学基金资助项目 !(946 35 5 )
关键词 胸腺因子D 免疫功能 生长发育 T3 GH T4 thymic factor D(TFD) immune growth hormone(GH) trilodothyroxine(T_3) thyroxine(T_4)
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  • 1Nicholas R. Hall,Joseph P. McGillis,Bryan L. Spangelo,David L. Healy,Allan L. Goldstein. Immunomodulatory peptides and the central nervous system[J] 1985,Springer Seminars in Immunopathology(1-2):153~164

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