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大鼠胰腺移植模型的建立 被引量:1

Establishment of a Rat Model of Pancreas Transplantation
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摘要 目的 建立大鼠胰腺移植模型。方法 采用经膀胱引流全胰腺十二指肠移植术式 ;带腹腔动脉和肠系膜上动脉的腹主动脉段与受体腹主动脉端侧吻合 ;供体门静脉与受体下腔静脉端侧吻合 ;胰腺外分泌经膀胱引流。结果  18只大鼠移植成功 ,早期移植胰腺血供良好。 Objective To establish a model of pancreas transplantation in rat. Methods The bladder drained whole pancreas duodenal transplantation model was adopted. The donor aortic segment including the celiac, superior mesenteric divergence were anastomosed with recipient abdominal aorta in end to side style. The donor portal vein was anastomosed to recipient inferior vena cava in end to side style. Pancreas exocrine secretion drainage was established with ureter drainage. Results Satisfactory results were obtained in 18 rats. Conclusion This method of the model for pancreas transplantation is reliable.
出处 《南京医科大学学报(自然科学版)》 CAS CSCD 2000年第4期299-300,共2页 Journal of Nanjing Medical University(Natural Sciences)
关键词 胰腺移植 动物模型 pancreas, transplantation models, biological
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  • 1顾相君,中华器官移植杂志,1984年,5卷,15页
  • 2Dr. Takahisa Kyogoku MD,Tadao Manabe MD,Takayoshi Tobe MD. Role of ischemia in acute pancreatitis[J] 1992,Digestive Diseases and Sciences(9):1409~1417

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  • 1Sakamaki F, Hoffmann H, Munzing S, et al. Effects of lung preservation solutions on PMN activation in Vitro. Transpl Int, 1999, 12 (2) :113-121.
  • 2Gale S C, Hokama J Y, Ritter L S, et al. Pentoxifylling reduces coronary leukocyte accumulation early in reperfusion after cold ischemia. Ann Thorac Surg, 2001, 71 (4) :1305-1311.
  • 3Kishi M, Tanaka H, Seiyama A, et al. pentoxifylling attenuates reperfusion injury in skeletal muscle after partial ischemia. Am J Physiol, 1998, 274 (5 Pt 2-) : H1435-1442.
  • 4吴强,曾祖荫.卡托普利对自发性高血压大鼠微血管稀少和内皮功能障碍的影响[J].微循环学杂志,1998,8(3):6-8. 被引量:2

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