摘要
目的 研究中药复方丙肝宁的保肝作用。方法 采用D Gal造成大鼠的急性肝损伤模型和CCl4 所致慢性肝损伤模型。结果 丙肝宁 2个剂量组对D Gal造成大鼠的急性肝损伤模型和CCl4 所致慢性肝损伤模型的血清酶活性均具有明显的抑制作用 (P <0 .0 5 ,P <0 .0 1) ,病理检查结果表明 ,丙肝宁 2个剂量组对D Gal造成大鼠的急性肝损伤模型和CCl4 所致慢性肝损伤模型的肝脏病理形态的改变具有明显的改善作用。
OBJECTIVE To study a complex prescription of Chinese herbs Bingganning 's protective effects on liver. METHOD D Gal was used to cause acute hepatic injury models while CCL 4 was adopted to induce chronic hepatic injury models in rats. RESULT Bingganning in two different dose groups were proved to have obvious inhibitive effects on the seroenzyme activity in both acute hepatic injury models and chronic hepatic injury models ( P <0.05, P <0.01).The pathological examinations showed that Bingganning in the different dose groups can remarkably improve the pathological changes in these two injury models. CONCLUSION Bingganning has protective effects on the experimental hepatic injury in rats.
出处
《南京中医药大学学报》
CAS
CSCD
2000年第4期214-216,共3页
Journal of Nanjing University of Traditional Chinese Medicine
基金
国家科委资助项目 !( 96 90 6 0 8 0 4)
关键词
丙肝宁
肝损伤
保肝作用
中医药疗法
Bingganning
D Gal
CCl 4
hepatic injury
protective effects on liver
