摘要
目的:探讨血清特异性IgE(sIgE)与皮肤点刺试验(SPT)强度的相关性及2种方法阳性率的差异性。方法:对109例临床症状和体征符合变应性鼻炎并且屋尘螨、粉尘螨和艾蒿SPT结果至少有1项为阳性的患者,进行屋尘螨、粉尘螨和艾蒿血清sIgE检测,并进行二者强度之间的相关性及阳性率差异性分析。结果:血清sIgE与SPT在检测屋尘螨、粉尘螨和艾蒿时强度均呈正相关(r=0.520、0.443、0.764,均P<0.01)。血清sIgE与SPT阳性率分别为屋尘螨55.0%、68.8%,粉尘螨54.1%、79.8%,艾蒿17.4%、27.5%;SPT阳性率比血清sIgE高,二者差异具有统计学意义(χ2=27.93、18.20、60.60,均P<0.01)。结论:血清sIgE与SPT强度之间具有很好的相关性,SPT更加敏感,但是二者之间不可相互替代,为了避免出现漏诊应提倡进行这2种实验室检查。
Objective：To investigate the correlation between serum specific immunoglobin E（slgE） and skin prick test（SPT） and their differences of the positive rate. Method：One hundred and nine patients with allergic rhinitis were detected the serum sIgE. The patients had positive symptoms and signs, positive SPT results with at least one allergen. Result： Specific IgE and SPT results of Dp, Df and Artemisia showed a positive correlation（r= 0. 520,0. 443,0. 764,P〈0. 01）. sIgE positive rates were 55. 0%,54.1% and 17.4% forDp,Dfand Artemisiare- spectively, whereas SPT positive rates were 68.8%, 79.8% and 27.5 % respectively. The difference between the positive rates of the slgE and SPT was significant（x^2 = 27.93,18.20,60.60, are P〈0.01）. Conclusion：There was a good correlation between specific IgE and SPT. SPT is more sensitive than sIgE, but SPT can not substitute for sIgE, vice versa.
出处
《临床耳鼻咽喉头颈外科杂志》
CAS
北大核心
2013年第2期75-77,80,共4页
Journal of Clinical Otorhinolaryngology Head And Neck Surgery
基金
北京市科技计划项目(No:65462-01)
关键词
屋尘螨
粉尘螨
艾蒿
皮肤点刺试验
特异性IGE
dermatophagoides farinaei dermatophagoides pteronyssinus
artemisia
skin prick test
serum specific IgE
