摘要
目的:探讨海口地区热带植物花粉中致敏花粉的种类,提高对热带地区花粉特异性症的诊断水平.方法:①在野外植物调查中,选择分布广、数量多、花粉量大的热带植物20种,鉴定科、属、种,盛花期采集花粉,由北京协和医院诊断试剂厂按照临床应用标准制成变应原.②2003年5月～2004年8月在我科就诊的变应性鼻炎、慢性荨麻疹、过敏性结膜炎、过敏性哮喘、过敏性咳嗽患者中,随机选用同意皮肤试验者500例,进行皮肤点刺试验和皮内试验,观察其致敏性.结果:20种热带植物花粉变应原临床皮肤过筛试验表明:5种花粉变应原阳性率超过50%;6种花粉变应原阳性率为40%～49%;3种花粉变应原阳性率为30%～39%;4种花粉变应原阳性率为20%～29 %;2种花粉变应原阳性率为10%～20%.结论:在热带地区进行植物调查,采集花粉制作变应原,通过临床皮肤过筛试验探明其致敏性,不但增加了热带花粉变应原品种,而且提高了对热带地区花粉症的特异性诊断水平.
Objective：To discover varieties of sensitization pollens and improve specific diagnosis against tropic pollinosis by the field survey of tropic plants. Method：①All of the chosen 20 tropic plants widely located, with enormous quantity and more pollens were identified the family, genus and species by specialists. And their pollens gathered in full bloom period were delivered to the chemical reagent works of union Hospital, Beijing and manufactured, according to clinical standards, into idiotoxins. ② Five hundred patients were chosen randomly from May, 2003 to August, 2004 among those who came to our department and were suffering from allergic rhinitis, slow urticaria, allergic taraxis, allergic asthma and deviancy asthma. They were aged 5-72, altogether 285 male and 215 female, and agreed to be observed. Experiments included skin pricking and intracutaneous test. Result：The 20 clinical skin prick tests of tropic plants pollens idiotoxin proved that the positive reaction rate was 5 of which was over 500/00, 6 of which 40%-49%, 3 of which 30%-39%, 4 of which 20%-29%, 2 of which 10%-20%,40%- 49%0. Conclusion：The tropic plants survey, pollen gathering, idiotoxin manufacturing, clinic intracutaneous test and sensitization discovery have not only increased varieties of tropic sensitization pollen idiotoxins but also improved specific diagnosis of pollinosis in tropic areas.
出处
《临床耳鼻咽喉科杂志》
CSCD
北大核心
2005年第22期1044-1045,共2页
Journal of Clinical Otorhinolaryngology
关键词
花粉
过筛试验
变应原
调查
Pollinosis
Sieve test
Idiotoxin
Survey
