摘要
目的:提供足月和近足月新生儿出生后120 h内的经皮胆红素(TcB)数据,并绘制新生儿TcB水平评估曲线图。方法:2009年8月至2012年1月在湖北省襄阳市妇幼保健院出生的2 373例新生儿中获得10 136个TcB值,所选新生儿胎龄≥35周,出生体重≥2 000 g,采用经皮胆红素仪(JH20-1C型)测量出生后6～120 h的TcB值,出生后24 h内每6 h测量1次,之后每12 h测量1次,每例新生儿至少有4次测量值,计算每一时段的TcB百分位数并绘制曲线图。结果:TcB百分位曲线图反映了新生儿自出生后至120 h内TcB水平,本研究经皮胆红素峰值出现时间为日龄3～5d,与国内部分研究资料相似,但百分位曲线值较高。结论:经皮小时胆红素水平用于评估新生儿高胆红素血症具有一定的价值,TcB百分位曲线图可用于对新生儿高胆红素血症进行有效的评估。
Objective： To provide the data on transcutaneous bilirubin（TcB） levels in the first 120 postnatal hours,and to develop an hour-specific bilirubin nomogram for term and near-term neonates.Methods： Ten thousand one hundred and thirty-six TcB values were collected from 2,373 neonates（gestational age≥35 weeks and birth weight≥2,000 g） who were born in our hospital from August 2009 to January 2012.All measurements were performed with the JH20-1C bilirubinometer at designated times from 6 to 120 postnatal hours.From the first postnatal day,TcB determinations were performed every 6 hours and thereafter every 12 hours up to the age of 120 hours.At least 4 measurements were obtained from each neonate.TcB percentiles for each designated time were calculated and used for the development of an hour-specific nomogram.Results： The TcB nomogram reflected the TcB levels in healthy neonates up to the 120 postnatal hours.In this study,transcutaneous bilirubin peak appeared in the third to fifth postnatal day.Conclusions： The hour-specific transcutaneous bilirubin nomogram was valuable in clinical application for evaluation of neonatal hyperbilirubinemia.
出处
《儿科药学杂志》
CAS
2013年第1期4-6,共3页
Journal of Pediatric Pharmacy
关键词
经皮胆红素
新生儿
高胆红素血症
Transcutaneous bilirubin
Neonate
Hyperbilirubinemia
