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下肢骨折手术麻醉前应用氯胺酮复合咪达唑仑镇痛效果观察 被引量:3

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摘要 目的:观察下肢骨折手术麻醉前应用小剂量氯胺酮复合咪达唑仑的镇痛效果。方法:选择下肢骨折50例,随机分为观察组和对照组各25例。观察组麻醉前静脉注射咪达唑仑和小剂量氯胺酮,对照组给予等剂量生理盐水。观察两组入室时、给药后、侧卧后和翻身平卧后的收缩压(SBP)、舒张压(DBP)、心率(HR)、血氧饱和度(SO2),以及两组镇痛效果。结果:观察组各时间节点SBP、DBP、HR水平显著低于入室时(P<0.05),对照组侧卧后和平卧后的SBP、DBP、HR水平显著高于入室时及给药后(P<0.05),观察组给药后及侧卧后的SBP、DBP、HR水平显著低于对照组(P<0.05);观察组SO2水平仅给药后时间点显著低于入室时和对照组给药后时间点(P<0.05)。观察组Ramasay镇痛评分为(2.2±0.1)分,显著高于对照组的(1.1±0.5)分(P<0.05)。结论:麻醉前应用小剂量氯胺酮复合咪达唑仑可有效缓解下肢骨折患者摆放椎管内麻醉体位时的疼痛,有利于更好地实施麻醉。
机构地区 解放军
出处 《人民军医》 2013年第1期51-52,共2页 People's Military Surgeon
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