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肝内胆管结石 被引量:13

Etiology and pathogenesis of hepatolithiasis
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摘要 肝内胆管结石是肝胆外科较为常见疾病,是非肿瘤性胆道疾病死亡的主要原因,其发生与环境因素、营养状态、胆道感染、胆汁淤积、病毒感染、寄生虫及胆管变异等因素有关,去除病灶、取尽结石、矫正狭窄、通畅引流、防止复发是该病的核心治疗原则.但肝内胆管结石病情复杂,病变部位广泛,手术并发症多,术后易复发,对肝脏及全身损害严重.因此,充分了解肝内胆管结石发病原因,采取有效措施降低该病的发生比治疗更为重要. Hepatolithiasis is a relatively common disease frequently encountered in department of hepa- tobiliary surgery. Intrahepatic stones are a major cause of mortality in patients with non-neoplastic diseases of the biliary tract. Environmental fac- tors, nutritional status, bile duct inflammation, biliary stasis, virus infection, parasites, and ana- tomic variation of the bile duct are involved in the pathogenesis of hepatolithiasis. Surgery is the main treatment for hepatolithiasis but is associ- ated with many serious postoperative complica- tions and relapse. Thus, it is important to fully understand the etiology of hepatolithiasis to take effective measures to prevent the disease.
出处 《世界华人消化杂志》 CAS 北大核心 2012年第34期3324-3328,共5页 World Chinese Journal of Digestology
关键词 肝内胆管结石 病因 发病机制 Hepatolithiasis Etiology Pathogenesis
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