摘要
放射性间质性肺炎 (radiationinterstitialpneumonia ,RIP)是临床上胸部肿瘤放疗、骨髓移植预处理及平时核辐射事故、战时辐射损伤后常见的一种并发症。尽管人们从各种角度对其进行了研究 ,也提出了许多观点 ,但迄今为止其发病机理仍然未被完全阐明。本文归纳总结了目前人们趋于接受的三种关于RIP发病机理的学说 ,即肺实质细胞靶细胞学说、肺间质浸润细胞参与学说与细胞因子介导学说 ,期望对该病的研究与临床治疗提供一些借鉴。
Radiation interstitial pneumonia (RIP) is a frequent complication in the radiotherapy of intrathoractic malignant tumors, pretreatment of bone marrow transplantation and accident of nuclear radiation. Despite accumulation of abundant information on RIP, its pathogenesis remains unknown up to now. This review sums up three hypotheses of RIP pathogenesis which are inclined to be accepted, these are hypotheses of lung parenchymal cells being the farget cells, involvement of lung interstitial infiltration cell and mediation by cytokine. [
出处
《军事医学科学院院刊》
CSCD
北大核心
2000年第2期140-142,共3页
Bulletin of the Academy of Military Medical Sciences
