摘要
目的探讨产前应用地塞米松对早产儿发生呼吸窘迫综合征(respiratory distress syndrome,RDS)的疗效影响。方法 114例早产儿根据孕妇产前是否给予地塞米松分为对照组(未给予地塞米松组55例)、观察组(给予地塞米松组59例),比较两组早产儿RDS发生情况,新生儿败血症和死亡情况,以及两组临床总有效率。结果观察组与对照组比较,RDS、新生儿败血症、死亡发生率均较低(P<0.01,P<0.05)。观察组出现RDS3例,治疗总有效率为100.0%,对照组出现RDS17例,治疗总有效率为70.6%,两组差异无统计学意义(P>0.05)。结论产前应用地塞米松可显著降低早产儿发生RDS,且能降低新生儿败血症的发生率和早产儿死亡率,值得临床推广使用。
Objective To research the curative effect of prenatal administration of dexamethasone on premature infant respiratory distress syndrome （RDS）. Methods One hundred and fourteen cases premature infant were divided into control group （55 cases） who was not given dexamethasone, and observation group （59 cases）, who was given dexamethasone. Occurrences of RDS, septicaemia and decease, total clinical effective rate about premature infant were compared between two groups. Results RDS, septicaemia and mortality rate of observation group were lower than that of the control group （P 0.01, P 0.05）. 3 cases of RDS were found in observation group, the total effect rate of the observation group was 100.0%. 17 cases of RDS were found in control group, the total effect rate of the control group was 70.6%. There was no significant difference （P 0.05）. Conclusion Prenatal administration of dexamethasone can significantly reduce premature infant RDS, septicaemia and mortality rate, which is worth to populate and apply.
出处
《中国当代医药》
2012年第34期64-65,共2页
China Modern Medicine
关键词
呼吸窘迫综合征
早产儿
地塞米松
疗效分析
Respiratory distress syndrom （RDS）
Premature infant
Dexamethasone （DXM）
Effect analysis
