摘要
本文报告广东省五个鼻咽癌普查现场组,以各自检测抗EB病毒VCA—IgA抗体的试剂盒,应用免疫酶法,同时检测中山市普查的180份正常人血清,各现场组的检测结果和中山市提供的血清的滴度,通过一致率和Kappa值计算,一致率(P0)为66—86％,Kappa值(K)为0.28—0.48,U为3.14—6.28,P<0.01。结果表明所得的K值均能排除因机遇所致的可能,其一致性是有意义的,从而提示各现场检测的抗EB病毒VCA—IgA抗体的阳性率可提供现场间的比较。 本文还对检测结果和可能影响VCA—IgA抗体检测一致性的因素进行了讨论。
An agreement examination for EBV VCA-IgA of 180 sera of normalperson sampled from serological mass screening of nasopharyngeal carcinoma (NPC) in Zh-ongshan city was carried out, Immunoenzymatic method was used on the same day and at the same place by 5 well trained expert doctors using their own diagnostic kit on EBV VCA-IgA from five different institintions for a mass screening of NPC in .Guangdong province. The agreement rate and Kappa value were calculated according to the detection results for each group compared with the liters of sera provided as standard by cancer institute of Zho-ongshan city. The observed agreement rate (Po) ranged from 66 to 86%, Kappa value 0.28 -0.48 and U varied from 3.14 to 6.28 .The agreement rates are significant. The result reveals that positive rate for EBV VCA-IgA antibody of five institutions may be compared each with others.
出处
《癌症》
SCIE
CAS
CSCD
北大核心
1991年第4期305-307,共3页
Chinese Journal of Cancer
关键词
EB病毒
VCA-IGA抗体
检查
Epstein-Barr virus VCA -IgA antibody the agreeament examination
