摘要
目的探讨手术治疗脊柱转移性肿瘤的临床效果。方法对2004年12月至2010年10月间深圳第二人民医院收治的47例脊柱转移性肿瘤患者,依据Tokuhashi脊柱转移瘤评分标准选择合适的手术方式,如肿瘤切除椎管减压内固定和人工椎体置换术等,比较患者治疗前后的疼痛强度视觉(VAS)评分、治疗3个月后的脊髓功能以及体力状况,跟踪随访并记录所有患者的生存时间。结果与治疗前VAS评分比较,患者手术后的疼痛程度明显降低,差异有统计学意义(P<0.05);脊髓功能及体力状态也有明显的改善,与治疗前比较,差异有统计学意义(P<0.05);随访3~49个月,中位生存时间为11.4个月。结论依据患者原发肿瘤类型及治疗前正确的评级,结合患者的临床状态,选择合理的手术方式,可以有效的治疗脊柱转移性肿瘤。患者疼痛症状改善明显,脊髓和体力状态有明显恢复,可以显著的提高患者的生存质量,提高生存率。
Objective To study the clinical effects of operation for spinal metastatic tumors.Methods 47 cases of spinal metastatic cancer patients from December 2004 to October 2010 were studied,acrossing to the Tokuhashi spinal metastases scoring system,select the appropriate surgical approach,such as tumor resection of spinal decompression and internal fixation,artificial vertebral body replacement surgery.Before and after treatment,The VAS pain score,spinal cord function and the physical status of patients were compared,followed up all the patients and recorded of all the survival time.Results After the treatment,VAS score was lower than before treatment,the pain in patients changed significantly,the differences were statistically significant(P0.05);The spinal cord function and physical status of patients were also changed significantly,the differences were statistically significant between before and after treatment(P0.05);All the patients were followed up 3 to 49 months,the median survival was 11.4 months.Conclusions In according to the correct rating for the patients with spinal metastatic tumors and the physical status of patients,we selected the reasonable surgery on treatment on spinal metastatic tumors,it made excellent effect,with significant clinical results,the pain,spinal cord and the physical status improved significantly,and the survival rate was also increased.
出处
《中国肿瘤临床与康复》
2012年第6期537-539,共3页
Chinese Journal of Clinical Oncology and Rehabilitation
关键词
手术
转移性肿瘤
脊柱
临床观察
Operation
Metastatic tumors
Spinal column
Clinical observation