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转录因子Snail与肿瘤关系的研究进展 被引量:5

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摘要 转录因子Snail在个体发育、器官纤维化和肿瘤发生发展中发挥着重要作用。在肿瘤发生发展中,Snail不仅是上皮细胞间充质转分化现象中关键的诱导子,而且在干细胞特性产生和维持、细胞生存和凋亡、以及免疫调节中起着重要作用。本文就转录因子Snail的结构和功能、Snail的调节途径以及Snail在肿瘤发生发展中的相关研究进展作一综述。
作者 罗邦雨 熊俊
出处 《癌变·畸变·突变》 CAS CSCD 2012年第5期393-396,共4页 Carcinogenesis,Teratogenesis & Mutagenesis
基金 国家自然科学基金项目(31101008) 第二军医大学研究生创新课题(SCMRC1105)
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