摘要
目的:分析前哨淋巴结活检(SLNB)在早期乳腺癌治疗中的应用价值。方法:2007-07-01-2011-05-27郑州大学第一附属医院乳腺外二科行SLNB 74例,选择其中61例最终行SLNB替代腋淋巴结清除(ALND)的病例资料为研究组,同期行ALND后病理检查确诊淋巴结≤1并有完整随访资料的83例临床T1～2N0～1M0期乳腺癌患者作为对照组。对比分析两组间术后并发症的差异。结果:74例行乳腺癌SLNB病例中,SLNB检出率为94.59%(70/74),假阴性率为2.86%(2/70);SLNB组的术后并发症患侧上肢水肿、疼痛和感觉障碍分别占8.2%、19.7%和13.1%,低于ALND组的25.3%、49.4%和40.9%,差异有统计学意义,P<0.05;SLNB组患侧与健侧上臂臂围差为(0.27±0.32)cm,ALND组为(0.79±0.04)cm,差异有统计学意义,P<0.05。结论:SLNB技术简便、安全、可靠、并发症少,对有SLNB适应证的患者,应首选SLNB。
OBJECTIVE： To analyze the application value of sentinel limb node biopsy （SI.NB） in early breast cancer. METHODS： Of all the 74 patients who received SLNB of the department of breast surgery Ⅱ in lhe first affiliated hospital of Zhengzhou university from July 1st 2007 to May 27th 2011, the 61 patients who received SLNB instead of ALND were selected as experimental group,selected 83 breast cancer patients who had complete follow-up data and received ALND of the corresponding period as control group,and whose pathology result of LN was no more than 1, and whom with a stage of T1-2 N0-1 M0. The difference of complications were compared between the two groups. RESULTS： Of all the 74 patients who received SLNB detection ratio was 94.59 % （70/74）, false negative rate was 2.86 % （2/70）. In the comparison of complications, such as lymph oedema, pain and sensory disturbance, the incidence of study group was lower than that of control group （P〈0. 05）. The difference of upper limb circumferences in study group was （0.27±0.32） crn,while that of control group was （0.79±0.04） cm,which was signifi- cantly different （P〈0. 05）. CONCLUSION： The technique of SLNB is simple, safe, reliable, and the complications are less. SLNB is the first choice for patients who have SLNB indication.
出处
《中华肿瘤防治杂志》
CAS
北大核心
2012年第20期1560-1562,共3页
Chinese Journal of Cancer Prevention and Treatment
