摘要
目的回顾性分析下肢动脉硬化性闭塞症(arteriosclerosis obliterans,ASO)介入治疗的临床疗效和通畅率。方法从2009年10月到2011年7月,32例(39条下肢)下肢ASO患者在上海交通大学附属第六人民医院行介入治疗。回顾性分析32例ASO患者的血管造影图像,根据病变长度和程度分级。对手术成功患者随访,随访期3~16个月,平均随访期(8.7±1.9)个月。随访期内每3个月进行一次下肢MRA或CTA检查,并搜集相关临床资料。结果技术成功率93%,踝肱指数(ankle-brachial index,ABI)从术前的0.47±0.11提高至术后的0.68±0.02,在随访期末20例取得了稳定疗效,总的通畅率为77%,保肢率为97%。结论介入治疗ASO安全可行,取得了良好的临床效果及通畅率,其长期疗效尚需进一步观察。
Objective To retrospectively evaluated the clinical efficacy of interventional revascularization for lower limbs arteriosclerosis obliterans (ASO). Methods From Oct 2009 to July 2011,32 patients (39 limbs) with lower limbs ASO performed interventional revascularization in our center. Angiography was retrospectively analyzed, and every lesion categorized and classified according to its length and severity. The mean follow up period was 3 - 162 months, mean 8.7 _+ 1.9 months. Lower limb magnetic resonance angiography (MRA) or computed tomography angiography (CTA) was per- formed every 3 months during follow-up. The clinical data were collected. Results 93% technical success rate was ob- tained. Ankle-brachial index (ABI) improved from 0. 47 + 0. 11 to 0.68 ± 0.02. At the end of follow up, 20 patients maintained a stable outcome, gained a 77% patency rate and 97% limb salvage rate. Conclusion Interventional revascu- larization is safe and feasible in the treatment of lower limbs ASO. With encouraging clinical outcome and patency rate, fur- ther research is warranted to evaluate long-term outcome.
出处
《临床放射学杂志》
CSCD
北大核心
2012年第12期1772-1776,共5页
Journal of Clinical Radiology
基金
上海市科委医学引导项目(编号:10411966700)
关键词
下肢
动脉硬化性闭塞症
内膜下成形术
介入治疗
Lower extremity Arteriosclerosis obliterans Subintimal angioplasty Interventional treatment