摘要
纤溶酶原激活物抑制物-1是丝氨酸蛋白酶抑制剂家族成员之一，是纤溶酶原激活物快速、专一、有效的生理抑制剂，可影响由组织型纤溶酶原激活物参与的纤溶过程，以及尿激酶型纤溶酶原激活物参与的生理病理条件下纤维蛋白溶解、细胞外基质循环、细胞迁移、组织修复、肿瘤浸润及转移等过程。
Plasminogen activator inhibitor-1 （PAI-1） is one of the members of the family of serine protease inhibitors, is fast, specific, effective physiological inhibitor of plasminogen activator, can affect process of fibrinolysis involved by tissue-type plasminogen activator, as well as fibrinolysis, extracellular matrix loops, cell migration,tissue repair,tumor invasion and metastasis process involved by urokinase-- type plasminogen activator under physiological and pathological conditions.
出处
《国际呼吸杂志》
2012年第24期1890-1893,共4页
International Journal of Respiration
