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帕罗西汀联合利培酮治疗甲基苯丙胺所致精神障碍的临床报告 被引量:7

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摘要 目的观察利培酮联合帕罗西汀治疗甲基苯丙胺所致精神障碍的疗效及不良反应,并与利培酮对照。方法将60例已诊断的甲基苯丙胺所致精神障碍患者随机分为两组:研究组采用利培酮联用帕罗西汀,对照组单用利培酮,每组各30例。采用简明精神病评定量表(BPRS)、大体功能评定量表(GAS)和不良反应量表(TESS)评定患者的精神病症状、疗效和不良反应。结果研究组总有效率为93.0%,对照组为90%,两组比较差异无显著性(P>0.05)。与对照组比较,研究组对焦虑抑郁控制较好,胃肠道反应较多,差异有显著性(P<0.01),两组其他不良反应比较差异无显著性。结论利培酮联用帕罗西汀与单用利培酮疗效相当,但利培酮联用帕罗西汀对有焦虑抑郁等症状控制较好,不良反应较轻。
出处 《中国医刊》 CAS 2012年第12期51-53,共3页 Chinese Journal of Medicine
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参考文献9

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