摘要
目的探讨雷贝拉唑、阿奇霉素、阿莫西林联合治疗消化性溃疡的临床疗效观察。方法将112例消化性溃疡患者随机分为治疗组和对照组(各56例),治疗组给予雷贝拉唑+阿奇霉素+阿莫西林治疗,对照组给予奥美拉唑+阿奇霉素+阿莫西林治疗。结果观察组总有效率为92.8%,明显优于对照组的76.8%,两组比较差异有统计学意义(P<0.05)。结论采用雷贝拉唑、阿奇霉素、阿莫西林联合治疗消化性溃疡疗效显著,具有使用方便、起效快、Hp根除率高等优点,且不良反应少,值得临床推广。
Objective To investigate the clinic effect observation of combined treatment of rabeprazole, azithromycin and amoxicillin on peptic ulcer. Methods 112 peptic ulcer patients were divided into observation group and control group in random （56 cases per group）. Rabeprazole, azithromycin and amoxicillin were used for observation group. Omeprazole, clarithromycin and amoxicillin were used for control group. Results The total effective rate of observation was 92.8%, obviously better than 76.8% of the total effective rate of control group. The difference between two groups was statistical significance （P 〈 0.05）. Conclusion The combined treatment effect of rabeprazole, azithromycin and amoxicillin on peptic ulcer is significant. The combined treatment is easy to use, produces rapid effect and has high HP eradication rate. Due to less untoward effect, it is worthy of clinical promotion.
出处
《中国医药科学》
2012年第24期88-89,共2页
China Medicine And Pharmacy
