摘要
目的观察奥美拉唑在幽门螺杆菌阳性的十二指肠球部溃疡治疗效果。方法 40例幽门螺杆菌阳性的十二指肠球部溃疡患者平分为两组,治疗组给予基于奥美拉唑的三联治疗方法,对照组给予基于埃索美拉唑的三联治疗方法。结果经过治疗后,治疗组总有效率为95.0%,对照组总有效率为75.0%,治疗组临床疗效明显好于对照组(P<0.05)。两组的Hp根除率分别为90.0%和75.0%,统计分析表明治疗组的根除率明显好于对照组(P<0.05)。两组不良反应情况对比无显著性差异(P>0.05)。结论奥美拉唑在幽门螺杆菌阳性的十二指肠球部溃疡治疗效果好,Hp根除多,安全性好,值得推广应用。
Objective To observe the effect of omeprazole in helicobacter pylori-positive duodenal ulcer treatment.Methods 40 patients with helicobacter pylori-positive duodenal ulcer were equally divided into two groups,the treatment group received omeprazole-based triple therapy,the control group received esomeprazole-based triple therapy.Results After the treatment,the total effective rate was 95.0% in the treatment group,the total effective rate was 75.0% in the control group,the clinical efficacy of the treatment group was significantly better than the control group（P〈0.05）.Hp eradication rate was 90.0% and 75.0% in the treatment group and the control group,the statistical analysis showed that the eradication rate in the treatment group was significantly better than the control group（P〈0.05）.There was no significant difference in adverse reactions of two groups（P〈0.05）.Conclusion Omeprazole in helicobacter pylori-positive duodenal ulcer treatment has good effect,more safet in Hp eradication rate,which is worthy of wide application.
出处
《临床医学工程》
2011年第5期689-690,共2页
Clinical Medicine & Engineering
