摘要
目的探讨美托洛尔缓释片治疗老年高血压伴心力衰竭患者的疗效。方法依据治疗方法不同将73例老年原发性高血压伴心力衰竭患者分为治疗组36例和对照组37例,对照组给予左旋氨氯地平治疗,治疗组在对照组基础上加用美托洛尔缓释片,3个月后观察临床疗效。结果两组疗效比较差异无统计学意义(P>0.05),治疗组VEGF和hs-CRP降低幅度均优于对照组,差异有统计学意义(P<0.05)。结论美托洛尔缓释片能够降低老年高血压伴心力衰竭患者的VEGF和hs-CRP指数,临床疗效显著,值得临床广泛应用。
Objective To explore the effect of metoprolol in treatment of elderly patients with heart failure and hypertension. Methods According to the different treatment methods, 73 elderly of primary hypertension with heart failure were divided into treatment group with 36 cases, and control group with 37 cases, Control group patients treated by left- handed amlodipine for treatment, the treatment group patients treated by metoprolol sustained-release tablets based on the control group, after observed the clinical effect after 3 months. Results The effect of two groups had no statistically significant （P 〉 0.05）, the VEGF and hs-CRP of treatment group were better than control group （P 〈 0.05）. Conclusion Metoprolol sustained-release tablets can reduce VEGF and hs-CRP index of hypertension elderly with heart failure patients, the clinical effect is distinct, it is worth clinical widely used.
出处
《中国医药科学》
2012年第24期77-78,共2页
China Medicine And Pharmacy
