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美托洛尔治疗慢性充血性心力衰竭临床观察

Clinical observation of therapy effects of metoprolol tablets on chronic heart failure
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摘要 目的观察美托洛尔治疗慢性充血性心力衰竭(CHF)的疗效。方法将80例CHF患者随机分为对照组和治疗组。对照组给予常规抗心力衰竭治疗;治疗组在对照组治疗基础上加用美托洛尔,起始量为6.25mg,2次/d,口服,2周后剂量加倍,最大剂量为50mg,2次/d,治疗4周和半年后进行比较。结果美托洛尔治疗组患者的心功能、心率、左室射血分数,与对照组相比,差异均有统计学意义(P<0.05)。结论在常规治疗基础上加用美托洛尔治疗CHF安全有效。 Objective To observe the clinical results of metoprolol tablets on chronic heart failure (CHF). Methods Eighty CHF patients were divided into two groups randomly. Control group (routine anti- CHF therapy ) and metoprolol treated group ( routine anti-CHF therapy and metoprolol tablets which were treated at 6.25 mg bid. at first,and then double dose after two weeks). The comparations were made at 4 weeks and half a year after therapy. Results Compared with controls, the heart function, heart rate and LVEF of metoprolol treated group is significantly different(P 〈 0.05). Conclusion On the base of routine anti-CHF therapy, the treatment of metoprolol tablets on CHF is safe and effctive.
作者 杨俊敏
出处 《中国实用医药》 2009年第2期38-40,共3页 China Practical Medicine
关键词 美托洛尔 心力衰竭 临床分析 疗效 Metoprolol tablets Heart failure
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