摘要
目的探讨舒芬太尼用于全麻术后苏醒期的效果。方法 2010年1月至2012年2月年进行全麻手术患儿89例,分为舒芬太尼组45例,对照组44例,观察两组效果。结果舒芬太尼组术后躁动评分(1.96±0.86)分,对照组术后躁动评分(3.58±1.32)分,经统计学分析有显著差异性(P<0.05)。结论舒芬太尼是芬太尼的衍生物,强效阿片类镇痛剂,是芬太尼5～10倍,镇痛时间持久,还有镇静作用;并且可以通过多种途径给药(静脉、鞘内及黏膜等),我们采取经鼻腔滴注用药,由于黏膜直接吸收入血,生物利用度高可以达到78%,可以在短时间内达到最佳镇痛作用,减少全麻苏醒期躁动。通过采取舒芬太尼鼻内滴入可以显著减少防范全麻苏醒期躁动发生,提高了手术、麻醉安全性,降低麻醉风险,是针对儿童全麻苏醒期躁动非常良好的方法 。
Objective To investigate the effect of sufentanil for anesthesia,postoperative recovery period.Methods From January 2010 to February 2012,89 cases of children with general anesthesia,is divided into the sufentanil group of 45 cases,control group,44 cases were observed effect.Results sufentanil group postoperative agitation score 1.96 ± 0.86,control group postoperative agitation score（3.58 ± 1.32）,significantly different by statistical analysis.Conclusion Sufentanil is a derivative of fentanyl,a potent opioid analgesic,fentanyl 5 to 10 times the duration of analgesia lasting,also sedative;and can be administered through a variety of channels（intravenous,intrathecal,and mucous membranes,etc.）,we take nasal drip medication due to the mucous membranes directly absorbed into the bloodstream,bioavailability can reach 78%,the best analgesic effect can be achieved in a short period of time,reducing anesthesia recovery period restlessness.By taking intranasal sufentanil can be significantly reduced to prevent the recovery from general anesthesia restlessness occurred improve the surgery anesthesia security,and reduce the risk of anesthesia,is method for children anesthesia restlessness very good.
出处
《中国实用医药》
2012年第32期21-22,共2页
China Practical Medicine
关键词
舒芬太尼
全麻术后苏醒期
效果观察
Sufentanil
Anesthesia postoperative recovery period
Effect observed
