右美托咪定对小儿七氟醚麻醉苏醒期不良反应的影响被引量：3

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摘要目的探讨右美托咪定对小儿七氟醚麻醉苏醒期不良反应的影响。方法 78例手术患儿,随机分为实验组和对照组,每组39例。两组均通过七氟醚进行麻醉,实验组患儿加用右美托咪定,对照组患儿加用等量的生理盐水。对比分析两组患儿的苏醒时间、苏醒后5 min以及拔管后1 min的动脉血压和心率水平,同时比较两组患儿的镇静满意度和躁动发生率。结果实验组患儿苏醒时间与对照组患儿相比差异无统计学意义(P>0.05)。实验组患儿苏醒后5 min动脉血压为(84.1±9.8)mm Hg(1 mm Hg=0.133 k Pa)、心率为(102.9±13.8)次/min;对照组患儿苏醒后5 min时动脉血压为(94.7±10.7)mm Hg、心率为(126.2±12.5)次/min。实验组患儿拔管后1 min动脉血压为(86.9±9.4)mm Hg、心率为(113.2±11.9)次/min;对照组患儿拔管后1 min时动脉血压为(97.5±10.8)mm Hg、心率为(131.7±12.8)次/min。实验组苏醒后5 min、拔管后1 min动脉血压和心率水平明显优于对照组,差异具有统计学意义(P<0.05)。实验组患儿镇静满意37例(94.87%)、躁动发生2例(5.13%);对照组患儿镇静满意25例(64.10%)、躁动发生10例(25.64%),实验组患儿镇静满意度和躁动发生率明显优于对照组,差异具有统计学意义(P<0.05)。结论右美托咪定能够有效降低小儿七氟醚麻醉苏醒期的躁动情况,平稳患儿的血压和心率,提升镇静满意度,值得临床广泛实施。

作者黄燕

机构地区江西省泰和县中医院

出处《中国现代药物应用》 2016年第24期93-94,共2页 Chinese Journal of Modern Drug Application

关键词右美托咪定小儿七氟醚麻醉苏醒期

分类号 R726.1 [医药卫生—儿科]

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