摘要
报道一种新型血液净化吸附剂交联琼脂包嵌凹凸律微囊(CAA)的制备、吸附特性及体外血相容性。CAA应用药用凹凸律为吸附剂,经琼脂包嵌交联微囊化,得到的珠状吸附材料包膜完好,能耐热压灭菌。用某些模型化合物及药物或毒物进行吸附试验,证明有较强的吸附性能,体外试验具有较好的血相容性。
A new method for preparation of cross-linked agar beads entrapped Attapulgite clay (CAA) is reported. Attapulgite clay was coated with agar and shaped in organic solvent, as well as cross-linked by epichlorohydrin. The products withstood autoclaving at 121℃ for 30 minutes and had a good adsorption ability for model compounds and medicines. The results of preliminary investigation indicate that CAA is relatively hemocompatible.
出处
《生物医学工程学杂志》
EI
CAS
CSCD
北大核心
2000年第2期235-237,共3页
Journal of Biomedical Engineering