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经尿道2μm激光前列腺剜除术与经尿道前列腺电切术治疗BPH的多中心比较研究 被引量:11

A multi-center comparative study on the transurethral prostate enucleation with 2 μm laser versus the transurethral resection prostatectomy in the treatment of benign prostatic hyperplasia
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摘要 目的:比较经尿道2μm激光前列腺剜除术与经尿道前列腺电切术(TURP)治疗BPH的疗效和安全性。方法:在三家医疗中心随机采用经尿道2μm激光前列腺剜除术和TURP两种手术方式治疗BPH患者各84例,比较分析两组患者术中及术后的相关临床指标。两组患者术前一般情况比较差异无统计学意义(P>0.05)。结果:三家医疗中心所有患者均手术成功。切除前列腺重量2μm激光组(19.96±13.57)g与TURP组(19.10±8.53)g比较,差异无统计学意义;2μm激光组手术时间(100.7±27.8)min显著大于TURP组(88.15±30.72)min(P<0.01);2μm激光组术中出血量(22.73±10.9)ml小于TURP组术中出血量(63.8±23.8)ml,两组间比较差异有统计学意义(P<0.01);所有患者术后国际前列腺症状评分、生活质量评分及最大尿流率均较术前明显改善(P<0.01)。结论:经尿道2μm激光前列腺剜除术与TURP治疗BPH近期疗效相当;2μm激光前列腺剜除术具有良好的止血效果,在手术中可更彻底切除增生前列腺组织,显著降低手术风险性,是一种治疗BPH安全、有效的微创手术方式。 Objective:To compare the therapeutic effects of the transurethral prostate enucleation with 2 μm laser and transurethral resection prostatectomy(TURP) for the treatment of benign prostatic hyperplasia (BPH). Method:One hundred and sixty-eight cases of BPH were divided into two groups randomly underwent transurethral prostate enucleation with 2μm laser and TURP in three hospitals. There were 84 cases in each group and was no significant difference between the two groups in some preoperative factors (P〉0.05). The clinic data were ana- lyzed. Result:All operation were successful. There was no significant difference in excised volume between 2 vm laser group (19.96±13.57) g and TURP group (19.10±8.53) g. The operation time of TURP (88.15±30.72) min was significant shorter than that for transurethral prostate enucleation with 2μm laser (100.7± 27.8)(P±0. 01). There were significant difference for blood loss during operation between 2 vm laser group (22.73± 10.9) ml and TURP group (63.8±23.8) ml(P〈0.01). The IPSS, QOL and Qmax were improved significantly after opera- tion in both groups (P〈0.01). Conclusion:The transurethral prostate enucleation with 2 μm is superior to TURP in safety, blood loss and resection thoroughness, and as efficacious as TURP. The transurethral prostate enucleation with 2 μm laser is a safe and effective minimally invasive treatment for BPH.
出处 《临床泌尿外科杂志》 2012年第12期927-930,933,共5页 Journal of Clinical Urology
基金 北京市特色临床医学技术发展研究项目(编号Z090507017709031)
关键词 良性前列腺增生 2ΜM激光 剜除术 经尿道手术 benign prostatic hyperplasia 2 micron lasers enucleation transurethral resection
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