摘要
目的 评价家庭长期氧疗 (HLTOT)对慢性阻塞性肺疾病 (COPD)患者生存期及生活质量的影响、医疗费用的耗费。方法 将我院呼吸内科同期住院及门诊病人随机分为HLTOT组 (36人 )、对照组 (32人 )。于治疗前病情稳定期及治疗后每年测定PaO2 、PaCO2 、FVC、FEV1、mPAP的数值。结果 (1)HLTOT组 2年内PaO2 、FEV1、mPAP与基础值比较均有显著性差异 (P <0 .0 5 )。PaO2 可长期维持较高水平 ,2年与 5年比较差异无显著性 (P >0 .0 5 ) ;(2 )HLTOT组 5年生存率 78% ,对照组 6 8% ,差异有显著性 (P <0 .0 5 )。结论 HLTOT使PaO2 长期维持较高水平 ,且无CO2 潴留的危险 ,初期可改变FEV1的下降率及降低mPAP 。
Objective To evaluate the effect of HLTOT on survival period,quality of life and medical cost in patients with COPD.Method The patients were divided into HLTOT group(n=36) and control group(n=32).Levels of PaO 2,PaCO 2,FVC,FEV 1,mPAP were determined before and after treatment every year.Results (1)In HLTOT group,levels of PaO 2,FEV 1,mPAP were significantly different from the basic value( P <0.05) within 2 years,but in PaO 2,there was no difference between the levels in 2 years and that in 5 years( P >0.05).(2)The 5 year survival rate(78%) in HLTOT group was significantly higher than that in control group(68%, P <0.05).Conclusions HLTOT can maintain higher level of PaO 2 in long term and has not danger of PaCO 2 retention.It can change the decline rate of FEV 1 and can decrease mPAP value.
出处
《现代诊断与治疗》
CAS
2000年第4期201-203,共3页
Modern Diagnosis and Treatment
关键词
家庭长期氧疗
慢性阻塞性肺疾病
氧分压
Home long term oxygen therapy
Chronic obstructive pulmonary disease
PaO_2
