摘要
研究诺氟沙星滴眼液稳定性 ,并预测其室温贮存有效期。方法 :采用紫外分光光度法测定诺氟沙星滴眼剂含量 ,采用初匀速法预测其有效期。结果 :诺氟沙星滴眼液稳定性好 ,室温 2 5℃贮存期 2 .5年。结论 :初匀速法预测药品有效期简便、省时 ,适用于医院制剂稳定性研究。
OBJECTIVE:To conduct stability study on norfloxacin eye drops at 25 ℃ and for predicting its expiry term.METHODS:Norfloxacin was determined by UV spectrophotometry,prediction of expiry by initial average rate methods.RESULTS:Stability of the eye drops is good,expiry term predicted at 25 ℃ is 2.5 years.CONCLUSIONS:Initial average rate methods is rapid,convenient and suitable for stability study of hospital preparations.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
2000年第6期347-348,共2页
Chinese Journal of Hospital Pharmacy
关键词
诺氟沙星
紫外分光光度法
滴眼液
稳定性
norfloxacin
UV spectrophotometry
initial average rate method
