期刊文献+

暴发性1型糖尿病酮症酸中毒伴急性一过性肝损伤1例 被引量:1

Fulminant T1DM ketoacidosis accompanied with acute transient liver injury:One case report
原文传递
导出
摘要 患者女,20岁,主因2010-02-28精神紧张及劳累后出现体重下降未予治疗后,又出现咳嗽、头痛、口干,多饮,伴头痛,恶心,呕吐、言语错乱,意识模糊等症状。患者入院后急查血糖,HI(血糖>33.3mmol/L)。动脉血气分析:pH 6.75,血钠122mmol/L,血钾6.6mmol/L,乳酸3.9mmol/L,尿酮(++)。诊断为暴发性1型糖尿病(F1D),酮症酸中毒,电解质紊乱,高钾低钠血症。经胰岛素治疗控制血糖,积极补液降糖降酶,同时保肝等治疗2周后患者血糖平稳,肝功能基本恢复正常经治疗后,血糖控制平稳,肌酶正常。 This 20-year-old female patient showed body weight declining for 2010-02-28, with mental tension and tiredness. She didn't have any treatment. Then she began to have cough, headache, thirst with desire to drink, nausea, vomiting, paraphasia, and confusion. After she was administered into our hospital, the laboratory tests showed that blood glucose 〉 33.3 mmol/L, arterial blood gas of pH 6.75, the blood sodium 122 mmol/L, blood potassium 6. 6 mmol/L, lactic acid 3. 9 mmol/L, and urine ketone + +. She was diagnosedas as fulminant TIDM (F1D), ketoacidosis, electrolyte disturbance, and hyperpotassemia and hyponatremia. With insulin treatment, liquid-supplementing, and liver-protecting, etc. , the level of her blood glucose became stable, her liver function was restored, and her muscular enzymes became normal.
出处 《中国糖尿病杂志》 CAS CSCD 北大核心 2012年第12期942-943,共2页 Chinese Journal of Diabetes
关键词 1型糖尿病 暴发性 肝损伤 Diabetes mellitus, type 1 (TIDM) Fulminant Liver injury
  • 相关文献

参考文献4

  • 1Sekine N,Motokura T, Oki T, et al. Rapid loss of insulin secre- tion in a patient with fulminant type 1 diabetes mellitus and car- banazepine hypersensitivity syndrome JAMA, 2001, 285:1153.
  • 2Sano H, Terasaki J, Tsutsumi C,et al. A case of fulminant type 1 diabetes mellitus after influenza B infection. Diabetes Res Clin Pract, 2008, 79:e8-e9.
  • 3Imagawa A, Hanafusa T, Miyagawa J, et al. A novel subtype of type 1 diabetes mellitus characterized by a rapid onset and an absence of diabetes-related antibodies. Osaka IDDM Study Group. N Engl Jmed, 2000, 342:301-307.
  • 4郑超,林健,杨琳,张贻宇,谭愈昱,杨亚玲,肖扬,车志宏,周智广.暴发性1型糖尿病的患病状况及其特征[J].中华内分泌代谢杂志,2010,26(3):188-191. 被引量:47

二级参考文献4

共引文献46

同被引文献14

  • 1Hamadi N, Mansour A, Hassan MH, Khalifi-Touhami F, Badary O. Ameliorative effects of resveratrol on liver injury in streptozotocin-induced diabetic rats. J Biochem Mol Toxicol 2012; 26: 384-392.
  • 2Schmatz R, Perreira LB, Stefanello N, Mazzanti C, Spanevello R, Gutierres J, Bagatini M, Martins CC, Abdalla FH, Daci da Silva Serres J, Zanini D, Vieira JM, Cardoso AM, Schetinger MR, Morsch VM. Effects of resveratrol on biomarkers of oxidative stress and on the activity of delta aminolevulinic acid dehydratase in liver and kidney of streptozotocin-induced diabetic rats. Biochimie 2012; 94: 374-383.
  • 3Kiss E, Kr?nzlin B, Wagenblaβ K, Bonrouhi M, Thiery J, Gr?ne E, Nordstr?m V, Teupser D, Gretz N, Malle E, Gr?ne HJ. Lipid droplet accumulation is associated with an increase in hyperglycemia-induced renal damage: prevention by liver X receptors. Am J Pathol 2013; 182: 727-741.
  • 4Martinovi? V, Grigorov I, Bogojevi? D, Petrovi? A, Jovanovi? S, Ili? M, Ivanovi? Mati? S. Activation level of JNK and Akt/ERK signaling pathways determinates extent of DNA damage in the liver of diabetic rats. Cell Physiol Biochem 2012; 30: 723-734.
  • 5Gobbo MG, Taboga SR, Ribeiro DL, Góes RM. Short-term stromal alterations in the rat ventral prostate following alloxan-induced diabetes and the influence of insulin replacement. Micron 2012; 43: 326-333.
  • 6Ludvigsson J, Carlsson A, Forsander G, Ivarsson S, Kockum I, Lernmark A, Lindblad B, Marcus C, Samuelsson U. C-peptide in the classification of diabetes in children and adolescents. Pediatr Diabetes 2012; 13: 45-50.
  • 7Besser RE, Shields BM, Hammersley SE, Colclough K, McDonald TJ, Gray Z, Heywood JJ, Barrett TG, Hattersley AT. Home urine C-peptide creatinine ratio (UCPCR) testing can identify type 2 and MODY in pediatric diabetes. Pediatr Diabetes 2013; 14: 181-188.
  • 8何晓顺,巫林伟,朱晓峰,王东平,鞠卫强,马毅,邰强,胡安斌,郭志勇,谈雅莉,韩明,王国栋,黄洁夫.腹部器官簇移植治疗终末期肝病合并胰岛素依赖的2型糖尿病五例[J].中华器官移植杂志,2011,32(5):260-263. 被引量:3
  • 9向静文,吴天梅,肖小敏.IADPSG糖尿病诊断新标准与现有诊断标准临床应用价值的比较[J].广东医学,2012,33(5):639-641. 被引量:22
  • 10翁厚光,曹维克,张迎梅,吴尚农.肝功能异常患者血清自身抗体检测对诊断自身免疫性肝病的意义[J].实用医学杂志,2012,28(11):1885-1887. 被引量:21

引证文献1

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部