摘要
目的探讨头孢曲松的不良反应(ADR)临床特点及影响因素。方法回顾分析2001年1月至2011年6月国内公开发表的有关头孢曲松ADR文献报道的个案190例,并对相关影响因素进行统计分析。结果头孢曲松ADR涉及多个器官和(或)系统,ADR发生率为3.05%,主要表现为消化系统反应42.11%和过敏反应32.11%;血液系统反应16.84%。结论应重视头孢曲松所致不良反应,头孢曲松大剂量、长疗程使用主要ADR为过敏反应、消化系统反应和血液系统反应。
Objective To discuss the adverse reactions of ceftriaxone（ADR） of clinical features and affecting factors.Methods A retrospective analysis of 2001 January to 2011 June China published ceftriaxone ADR case 190 cases reported in the literature,and the correlative factors analysis.Results Ceftriaxone ADR involving multiple organs and（or） system,the incidence of ADR was 3.05%,mainly for the digestive system reaction 42.11% and allergic reaction of 32.11%;hematologic response 16.84%.Conclusion Great importance should be attached to ceftriaxone induced adverse reactions,ceftriaxone dose,long course of treatment using ADR as an allergic reaction of digestive system,blood system reaction and reaction.
出处
《中国实用医药》
2012年第31期165-166,共2页
China Practical Medicine
关键词
头孢曲松
不良反应
临床分析
Ceftriaxone
Adverse reactions
Clinical analysis
