期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

区域性动脉灌注化疗对胰腺癌淋巴结转移的影响

Effects of chemotherapy via regional arterial perfusion on lymph node metastasis of pancreatic cancer
原文传递
导出
摘要 区域性动脉灌注化疗（RAIC）作为胰腺癌综合治疗的有效手段，不仅可提高胰腺癌局部的药物浓度，降低全身不良反应，提高耐受性，从而保证足够的给药剂量，还有可能提高胰腺区域内淋巴结内的药物浓度，减少淋巴结转移的发生，但胰腺癌RAIC作用机制和对胰腺癌淋巴结转移的影响有待进一步研究。 Regional arterial intra chemotherapy （RAIC） was an effective method of combined therapy for pancreatic carcinoma, which could elevate the regional concentration of antieancer agents for sufficient dosage in pancreas, reduce the systemic adverse events, increase the toler ation of chemotherapy. It could also increase the concentration of anticancer agents in regional lymph node of pancreas, thus decrease the lymph node metastasis. The mechanism of RAIC for pancreatic cancer and the impact for lymph node metastasis needed to be further investigated.
作者 许文彦 傅德良
机构地区 复旦大学胰腺病研究所复旦大学附属华山医院普外科
出处 《中华肝胆外科杂志》 CAS CSCD 北大核心 2010年第3期232-234,共3页 Chinese Journal of Hepatobiliary Surgery
关键词 胰腺癌 区域性动脉灌注化疗 淋巴转移 pancreatic cancer Regional arterial intra-chemotherapy（RAIC） lymphatic metastasis
分类号 R735.9 [医药卫生—肿瘤]
  • 相关文献

参考文献25

  • 1Jemal A,Siegel R,Ward E,et al.Cancer statistics,2007.CA Cancer J Clin,2007,57:43-66.
  • 2Pawlik TM,Gleisner AL,Cameron JL,et al.Prognostic relevance of lymph node ratio following pancreaticoduodenectomy for pancreatic cancer.Surgery,2007,141:610-618.
  • 3Fortner JG,Klimstra DS,Senie RT,et al.Tumor size is the primary prognosticator for pancreatic cancer after regional pancreatectomy.Ann Surg,1996,223:147-153.
  • 4Egawa S,Takeda K,Fukuyama S,et al.Clinicopathological aspects of small pancreatic cancer.Pancreas,2004,28:235-240.
  • 5Bogoevski D,Yekebas E,Schurr P,et al.Mode of spread in the early phase of lymphatic metastasis in pancreatic ductal adenocarcinoma:prognostic significance of nodal microinvolvement.Ann Surg,2004,240:993-1001.
  • 6倪泉兴,傅德良,蒋永剑,张群华,姚琪远,虞先浚,张延龄.胰头癌淋巴转移特点的探索和影响的因素[J].中华肝胆外科杂志,2004,10(4):231-234. 被引量：20
  • 7Alfred CJ,Munther A.Adenocarcinoma of the head of the pancreas:effects of surgical and nonsurgical therapy.Am Surg,1999,65:1143-1149.
  • 8Schwarz RE,Smith DD.Extent of lymph node retrieval and pancreatic cancer survival:information from a large US population database.Ann Surg Oncol,2006,13:1189-1200.
  • 9Pawlik TM,Gleisner AL,Cameron JL,et al.Prognostic relevance of lymph node ratio following pancreaticoduodenectomy for pancreatic cancer.Surgery,2007.141:610-618.
  • 10Brown HM,Ahrendt SA,Komorowski RA,et al.Immunohistochemistry and molecular detection of nodal micrometastases in pancreatic cancer.J Surg Res,2000,95:141-146.

二级参考文献32

  • 1钟守先.积极开展胰头癌根治术——为提高五年生存率而努力[J].中华肝胆外科杂志,1998,4(5):267-268. 被引量：14
  • 2Sener SF, Fremgen A, Menck HR, et al. Pancreatic cancer: a report of treatment and survival trends for 100 313 patients diagnosed from 1985-1995,using the national cancer database. J Am Coll Surg,1999,189:1-7.
  • 3Kayahara M, Nagakawa T, Kobayashi H, et al. Lymphatic flow in carcinoma of the head of the pancreas. Cancer,1992,70:2061-2066.
  • 4Nagakawa T, Kobayashi H, Ueno K,et al. Clinical study of lymphtic flow to the paraaortic lymph nodes in carcinoma of the head of the pancreas. Cancer,1994,73:1155-1162.
  • 5Ishikawa O, Ohigashi H, Sasaki Y, et al. Practical grouping of positive lymph nodes in pancreatic head cancer treated by an extended pancreatectomy. Surgery, 1997,121:244-249.
  • 6Deki H, Sato T. An anatomic study of the peripancreatic lymphatics. Surg Radiol Anat, 1988,10:121-135.
  • 7Nagakawa T, Kobayashi H, Ueno K, et al. The pattern of lymph node involvement in carcinoma of the head of the pancreas. Int J Pancreatol, 1993,13:15-22.
  • 8Kagahara M, Nagakawa T, Ohta T, et al. Analysis of paraaortic lymph node involvement in pancreatic carcinoma. Cancer, 1999,85:583-590.
  • 9Furukawa H, Okada S, Saisho H, et al. Clincopathological features of small pancreatic adenocarcinoma. Cancer, 1996,78:986-990.
  • 10钟守先，中国肝胆外科杂志，1998年，35卷，4期，267页

共引文献123

中华肝胆外科杂志
2010年 第3期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部