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抽动-秽语综合征脑诱发电位的研究 被引量:2

SENSORY EVOKED POTENTIAL IN TOURETTE SYNDROME
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摘要 目的 :观察抽动 -秽语综合征 ( TS)脑诱发电位电活动变化。 方法 :TS 40例和对照组 32例进行了脑诱发电位检查。 结果 :视觉诱发电位 ( VEP) TS组 T2 、N2 波潜伏期比对照组显著延长 ( P<0 .0 5) ,VEP轻度异常占 30 % ,中度异常占 1 5% ,异常率为 45%。脑干听觉诱发电位 ( BAEP) TS组 - 、 - 波峰间期比对照组显著延长 ( P<0 .0 5) ,BAEP轻度异常占 1 7.5% ,中度异常占 5% ,重度异常占 2 .5% ,异常率为 2 5%。体感诱发电位 ( SEP) TS组轻度异常占 50 % ,中度异常占 2 7.5% ,异常率为 77.5%。结论 :提示抽动 -秽语综合征患儿脑功能受到损害 ,损害部位涉及整个大脑及中枢脑干 ,但体格发育没有受到影响。 Objective: To observe the changes of evoked potential of the brain in Tourettes syndrome(TS).Methods: Fourty patients with TS and 32 normal children were studied in sensory evoked responses. Results: Compared with the normal group, P 2 and N 2 latencies were prolonged significantly(P<0.05) in visually evoked potential(VEP), 18 cases(45%) in total showing abnormal VEP;Ⅰ Ⅲ,Ⅰ Ⅴ waves interpeak latencies were significantly pronlonged(P<0.05) in brainstem auditory evoked potential(BAEP),with 10 cases(25%) showing abnormal BAEP; N 3 latency was significantly prolonged (P<0.02) in somatosenaory evoked potential(SEP), 31 cases (77.5%) in total showing abnormal SEP. The percentage of P 3,N 2 amplitude reduction and P 3,N 2 absense were the highest in SEP. There were positive correlations between age, height and weight(P<0.01). Conclusion: The brain function was effected, involving the entire brain and brainstem, but the physique develepment was not affected.
出处 《山东医科大学学报》 2000年第1期20-22,25,共4页 Acta Academiae Medicinae Shandong
关键词 秽语综合征 诱发电位 视觉 听觉 Tourette Syndrome Evoked potential, visual Evoked potential, brainstem auditory Evoked potential, somatosensory
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  • 1杨健,杨文民,王明慧,许克铭.脑瘫小儿脑干和体感诱发电位的改变[J].北京医学,1995,17(3):148-150. 被引量:1
  • 2姜玉华 孙若鹏.抽动秽语综合征的临床表现及病因学探讨[J].临床儿科杂志,1998,16(3):210-210.
  • 3崔志杰.抽动秽语综合征患儿事件相关电位及行为评价[J].中华儿科杂志,1992,30(6):365-365.
  • 4American Psychiatric Association . Diagnostic and statis-tical manual of mental disorder.4thed(DSM-IV). Washington DC-American Psychiatric Association,1994:100.

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