小儿传染性单核细胞增多症70例临床特点分析被引量：1

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摘要收集我院2007～2012年收治的70例传染性单核细胞增多症患儿的临床资料,分析患者的发病原因、临床表现、并发症及预后。结果在本组资料中,传染性单核细胞增多症患儿以发热、咽峡炎、颈淋巴结肿大、肝脾肿大等临床表现最为多见,患儿发病多与EB病毒感染有关,变异淋巴细胞增高是诊断传染性单核细胞增多症简便有效的筛查手段,但与患者病情、预后无明显相关性,EBV-VCA-IgM的阳性率与病程、预后等因素有关。传染性单核细胞增多症具有典型的临床表现,能累及多种器官、系统,提高本病实验室检查特点的认识有助于减少误诊及判断患者的预后。

作者杨秀榕

机构地区深圳市龙岗区人民医院儿科

出处《现代诊断与治疗》 CAS 2012年第9期1537-1538,共2页 Modern Diagnosis and Treatment

关键词传染性单核细胞增多症临床特征 EB感染

分类号 R512.7 [医药卫生—内科学]

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参考文献7

1洪冬玲,李强,贾苍松.儿童传染性单核细胞增多症332例临床分析[J].中国实用儿科杂志,2003,18(12):723-726. 被引量：57
20kan M.Ovenriew and pmblematie standpoints of severe chmnieae- tire Epsteir-Ba I1 vims ir Il ction syndrome[J].Crit RevOncol Hema- tol, 2008, (44) : 273-282.
3李强.EB病毒感染相关性疾病[J].临床儿科杂志,2005,23(4):248-250. 被引量：27
4郭小玲,傅四毛,张志培.肺炎支原体感染并发传染性单核细胞增多症6例临床分析[J].中国实用儿科杂志,2002,17(8):462-463. 被引量：27
5Tomkinson BE,Wagner DK,Nelson DL,et al.Activated lym-pho- cytes during acute Epstain-Barr vimse infction [J].J Immu-nol, 1987,139(11) :3802-3807.
6雷春莲.流式细胞术检测淋巴细胞亚群的研究[J].中国实用儿科杂志,1994,9(5):284-285. 被引量：15
7Fanslow WC.Anderson DW.Grabstein KH.et al.soluble forms of CD40 inhibitbiologic responses of human B ceils [J].The Journal of Immunology, 1992,149(2) :655-660.

二级参考文献18

1吴瑞萍胡亚美.实用儿科学（第6版）[M].北京:人民卫生出版社,1996.676.
2王慕逖王韵琴等.儿科学（第4版）[M].人民卫生出版社,1998.232.
3Kawa K.Diagnosis and treatment of Epstein-Barr virus-associated natural killer cell lymphoproliferative disease.Int J Hematol,2003,78(1):24-31.
4Straathof KC,Bollard CM,Rooney CM,et al.Immunotherapy for Epstein-Barr virus-associated cancers in children.Oncologist,2003,8(1):83-98.
5Sayos J,Wu C,Morra M,et al.The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM.Nature,1998,395:462-469.
6Kasahara Y,Yachie A.Cell type specific infection of Epstein-Barr virus(EBV) in EBV-associated hemophagocytic lymphohistiocytosis and chronic active EBV infection.Crit Rev Oncol Hematol,2002,44(3):283-294.
7Taieb A,Plantin P,Du Pasquier P,et al.Gianotti-Crosti syndrome:a study of 26 cases.Br J Dermatol,1986,115(1):49-59.
8Rickinson AB.Chronic symptomatic Epstein-Barr virus infection.Immunol Today,1986,7:13-14.
9Kawa K.Epstein-Barr virus associated disease.Minophagen Med Rev,1999,44:1-13.
10Nakagawa A,Ito M,Saga S.Fatal cytotoxic T-cell proliferation in chronic active Epstein-Barr virus infection in childhood.Am J Clin Pathol,2002,117(2):283-290.