摘要
用四氯化碳对妊娠小鼠及其胎鼠进行微核试验 ,结果表明 ,以 16 mg/ kg四氯化碳作为注射剂量处理妊娠小鼠时 ,母鼠骨髓和胎肝血嗜多染红细胞微核率分别为 2 .96± 0 .36 ,12 .75± 0 .76 ,与正常组两种微核率 (0 .89± 0 .18,5± 0 .2 5)相比较 ,差异均非常显著 (p<0 .0 1) ,这说明四氯化碳具有一定的诱变活性 .
The effect of carbon tetracholoride on preganant and uwiparous mice was tested by micronucleus test. When 16mg/kg carbon tetrachloride was injected, into preganant mice the micronucleus rate of marron and liver nucleli were 2.96±0.36、12.76±0.76 respecitively. Which were 0.89±0.18 and 5±0.25 separately in control group. The discrepancy was obvious (P<0.01). It could be concluded that carbon tetrachloride ned mutagenic effect to some degree.
出处
《新疆大学学报（自然科学版）》
CAS
2000年第2期74-75,共2页
Journal of Xinjiang University(Natural Science Edition)
