摘要
目的研究老年人良性前列腺增生（BPH）的诊断治疗情况。方法以2010年1月至2012年3月在干部门诊体检的188例保健干部为对象，对其进行腹部超声检查测定前列腺体积（PV），以PV≥20ml诊断BPH；国际前列腺症状评分（IPSS）评估下尿路症状；测定血清前列腺特异性抗原（PSA），将年龄≥62岁、PsA≥1．6μg／L、PV≥31ml诊断为高进展性BPH。分析老年人BPH患病率、知晓率及治疗情况，单因素方差分析比较不同年龄组的PV、IPSS及PSA浓度，Logistic回归分析BPH的危险因素。结果188例老年人BPH的患病率为48．4％（91／188），知晓率41．5％（78／188），但因下尿路症状而就诊知晓的为10．6％（20／188）；PV、IPSS、PSA浓度随增龄而增加（均P〈0．01），年龄、高血压及糖尿病是BPH的危险因素；BPH患者中以5a还原酶抑制剂为主进行药物治疗的占47．3％。46例高进展BPH患者中有10例未使用药物治疗。结论BPH患病率随增龄而增加，老年人对下尿路症状不够重视导致主动就诊率低，临床医师对高进展性BPH药物治疗不及时，应在老年、高血压和糖尿病患者中加强BPH宣教及筛查，采取综合性治疗措施。
Objective To evaluate the diagnostic and therapeutic status of elderly benign prostatic hyperplasia （BPH）. Methods Totally 188 male elderly in outpatient department from January 2010 to March 2012 were enrolled in this study. Medical history was inquired in detail, and prostatic volumes （PV）were measured by abdominal ultrasound, PV≥ 20ml was diagnosed as BPH. Lower urinary tract symptoms （LUTS） was evaluated by international prostate symptom score （IPSS）, prostate specific antigen （PSA） was measured. Age≥62 years, PSA≥1. 6 μg/L and PV≥31 ml were considered as higher risk of clinical progression of BPH. We investigated the rate of prevalence, awareness and treatment of BPH. PV, IPSS and PSA were compared among different age groups by ANOVA. Logistic regression analysis was made to show the risk factors of BPH. Results Among 188 male elderly, the prevalence rate of BPH was 48.4%, and the total rate of awareness was 41.5%. The rate of awareness resulting from seeing doctor due to LUTS was 10.6%00. PV, IPSS and PSA were increased with ageing. Risk factors contributing to BPH were age, hypertension and diabetes. The treatment rate with drugs of 5a-reductase inhibitor was 47.30%, however 10 subjects had not been given drugs treatment among 46 patients with higher risk of clinical progression of BPH. Conclusions The prevalence rate of BPH is increased with ageing, the proportion of seeing a doctor witla passion is loveer because the male elderly have not paid enough attention to LUTS. And doctors have not given drugs intervention to patients with clinical progression BPH in time. We should launch propaganda and education among the elderly patients with hypertension and diabetes and take comprehensive treatment.
出处
《中华老年医学杂志》
CAS
CSCD
北大核心
2012年第11期943-946,共4页
Chinese Journal of Geriatrics
关键词
前列腺增生
前列腺特异抗原
Prostatic hyperplasia
Prostate-specific antigen
