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^(99m)Tc-MIBI盆腔显像诊断卵巢恶性肿瘤的临床研究 被引量:1

The clinical study of ^(99m)Tc MIBI imaging for detecting ovarian malignant tumor
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摘要 目的 :对 70例盆腔肿物患者进行 99m Tc-甲氧基异丁基异腈 ( MIBI)显像 ,以探讨其对卵巢恶性肿瘤的诊断价值。方法 :所有受检者于检查当日晨禁食。静脉注射 99m Tc- MIBI3 70~ 72 0 MBq后 ,分别于 5 ,15 ,3 0及 60分钟采集早、晚期下腹及盆腔前位图像各一帧。所有结果均有手术、活检或穿刺组织病理学检查做对照。结果 :2 0例卵巢恶性肿瘤中 17例有放射性填充 ( 85 % ) ,而 2 6例卵巢良性肿瘤中仅 3例有放射性填充 ( 11.5 % )。 4例腹腔内其他部位恶性肿瘤全部阳性 ,11例盆腔炎性包块仅 1例阳性 ,子宫肌瘤对照组中有 3例阳性。诊断灵敏度及特异性分别为 87.5 %及 84 .7%。结论 :99m Tc- MIBI盆腔显像对卵巢恶性肿瘤的术前诊断及盆腔肿瘤的鉴别诊断具有较高的灵敏度及特异性 。 Objective:To evaluate the value of the pelvic masses 99m Tc MIBI imaging for detecting malignant tumor of ovary. Methods:70 patients with pelvic mass were studied using 99m Tc MIBI. Each patients was fasted for more than 6 hours to slow down movement of tracer in digest tract. After an intravenous injection of 370~720 MBQ 99m Tc MIBI, planar images of pelvic and lower abdomen was taken at 5, 15, 30 and 60 minutes Final histopathologic diagnosis was achieved through surgical extrirpation, excisional biopsy or transcutaneous needle biopsy. Results:Radioactivity was observed in 17 out of 20 ovarian malignant tumors (85%), while in 26 ovarian benign lesions, only 3 with radioactivity (11 5%). The imaging results were all positive in 4 patients who had abdomen malignancies. In 11 pelvic inflammations and 9 uterin leomas, only 1 and 3 showed 99m Tc MIBI uptake. The sensitivity and specificity were 87.5% and 84.7%. Conclusion: 99m Tc MIBI is useful in differentiating benign and malignant pelvic masses in gynecologic patients.
出处 《军医进修学院学报》 CAS 2000年第1期26-28,共3页 Academic Journal of Pla Postgraduate Medical School
基金 "九五"军队科研基金!项目 ( 96 Z0 5 5
关键词 卵巢肿瘤 贫腔显像 ^99MTC-MIBI m Tc MIBI ovarian carcinoma
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  • 1沈钰如,国外医学放射医学核医学分册,1993年,17卷,282页
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