摘要
感染是临床上常见的病症,有效治疗的关键在于快速而准确地进行病原学诊断。降钙素原是降钙素的前体物质,作为一种炎性介质在细菌或真菌感染合并严重全身系统反应或器官低灌注时显著升高,而在病毒或局灶感染时水平正常或轻度升高,近年来成为鉴别细菌感染和其他病原体感染的新型标志物。现就其生物学特性、测量方法及临床应用予以综述。
Infection is a common disease,and the key to effective treatment is rapid and accurate diagnosis of pathogen.Procalcitonin,the precursor of calcitonin,as a mediator of inflammation,increases markedly in bacterial or fungal infection with severe system reaction or organ hypoperfusion,but is normal or elevates mildly in virus or focal infection.It has become a new marker for identification of bacterial infections and other pathogens.Here is to make a review on the bionomics,measurements,and clinical application of procalcitonin.
出处
《医学综述》
2012年第21期3565-3567,共3页
Medical Recapitulate
关键词
降钙素原
感染
炎性介质
Procalcitonin
Infection
Inflammatory medium