摘要
目的探讨降钙素原在败血症诊断中临床应用价值。方法收集我院败血症患者60例,局部细菌感染患者60例,于入院第1天采集患者血清,测定白细胞(WBC),中性粒细胞比例(Neu%),C-反应蛋白(CRP)和降钙素原(PCT)水平。结果败血症患者主要以革兰阴性杆菌感染为主(47/60);局部细菌感染者以革兰阳球细菌为主(43/60)。败血症患者组的Neu%、CRP和PCT水平明显高于局部细菌感染组,差异有统计学意义(P均<0.01)。PCT的ROC曲线下面积(AUC)明显高于其他指标,PCT用于诊断感染患者中败血症的发生的敏感性为83.3%,特异性为86.7%。结论 PCT诊断感染患者中败血症的灵敏度、特异性均较高,有很高的临床应用价值。
Objective To study the value of procalcitonin in septicemia. Methods A total of 60 patients with sepsis, 60 local intection patients from our hospital, the level of white blood cell（WBC）, neutrophil ratio（Neu%）, C -reactive pro-tein（CRP） and procalcitonin （PCT） were observed on the first day of enrollment. Results Patients with sepsis were main infection with Gram-negative bacilli （47/60）; local intection patients were main infection with gram positive coccus（43/60）. Patients with sepsis had a higher level of Neu%、CRP and PCT than local intection patients（all P〈0.01 ）. The area under the curve of ROC of PCT was significantly larger than others. The sensitivity and specificity of PCT was 83.3%and 86.7% respecitively on diagnosis of septicemia. Conclusion PCT has higher sensitivity and specificity than WBC、Neu%and CRP. PCT has high clinical value in septicemia.
出处
《中国现代医生》
2014年第25期67-69,共3页
China Modern Doctor
