摘要
【目的】调查 5 0岁以上的中老年人群中的原发闭角性青光眼患病率。【方法】 1997年在广东省斗门县以村为单位 ,通过重组随机整群抽样确定检查对象 ,用ETDRS视力表检查裸眼视力、常戴镜视力和针孔视力 ,Schiotz计测定眼压 ,直接电眼底镜作视神经垂直C/D比的估计 ,手电筒侧照法和vanHerrick法测定前房深度 ,并结合急性发作史、前房角镜和视野检查作出诊断。【结果】在 5 34 2名实检对象 (受检率 92 7% )中 ,青光眼是第 5位致盲眼病。原发闭角性青光眼的患病率为1 0 % ,男性和女性中分别为 0 8%和 1 2 % ,在 5 0～ 5 9、6 0～ 6 9和 70～ 98岁年龄组中分别为 0 4%、0 8%和 1 6 % ,浅前房人群中为 5 9% ,经logistic回归校正混杂作用后 ,年龄和前房深度为独立的危险因素 ,以 5 0岁年龄组和深前房者为基准 ,70～ 98岁年龄组和浅前房者的调整比数比分别为 3 3和 11 3。【结论】原发闭角性青光眼是人群中重要的致盲眼病 ,老年和浅前房者是危险人群。
Objective To estimate the prevalence of primary angle closure glaucoma(PACG) in elderly population(older than 50 years). Methods The subjects were identified by clustering samplings scheme in Doumen County (China) in 1997. Visual acuities, including naked eye, presenting and pinhole visual acuity, were measured by ETDRS visual chart. Intra ocular pressure measurement by Schiotz tonometer, vertical C/D ratio assessment by direct electric ophthalmoscopy were also carried out. The depth of anterior chamber (DAC) was estimated by pen light oblique illumination scheme and van Herrick technique. Final diagnosis was made after further considering the onset history, gonioscopy and visual field examination. Results In 5 342 examined subjects with response rate of 92.8%, glaucoma ranked at the fifth leading cause of blindness. The prevalence of PACG was 1.0%(male 0.8%,female 1.2%). Prevalence was 0.4%, 0.8% and 1.6% in the 50～59, 60～69 and 70～98 years old group respectively. 5.9% of individuals with shallow anterior chamber were diagnosed as PACG. After adjusting the confounding effects with logistic regression model, age and DAC were independent risk factors while sex was no more significant. Comparing with 50～59 and deep anterior chamber, the adjusted odds ratio of 70～98 years old group and shallow anterior chamber subjects were 3 3 and 11 3 respectively. Conclusions PACG remains as the main cause of blindness in elderly population. Elderly people with shallow anterior chamber are significant risk population.
出处
《中山医科大学学报》
CSCD
2000年第3期212-214,232,共4页
Academic Journal of Sun Yat-sen University of Medical Sciences
基金
世界卫生组织和国际狮子会资助
中山医科大学中山眼科中心
美国国家眼科研究所 !(NEI/NIH)
"广东省斗门县眼病调查"部分结果
