摘要
目的探讨高同型半胱氨酸血症(Hhcy)与青年女性缺血性卒中的关系。方法分析43例青年女性缺血性卒中患者的血清同型半胱氨酸(Hcy)水平,与同期45例青年女性非脑血管病患者进行比较;卒中组患者根据脑梗死灶面积大小分为3个亚组比较组间血清Hcy的差异。结果卒中组血清Hcy水平明显高于对照组(P<0.05);卒中组患者亚组间血清Hcy水平差异无统计学意义(P>0.05)。结论 Hhcy是青年女性缺血性卒中的一个重要危险因素,临床应将血清Hcy作为青年女性缺血性卒中的一项常规检测项目。
Objective To investigate the correlation between hyperhomocysteinaemia（Hhcy）and ischemic stroke in young women on ischemic stroke in young women. Methods A case-control study was performed. A total of 43 young women with acute ischemic stroke who were admitted to the Department of Neurology in Hebei Provincial People＇s Hospital from January 2011 to April 2012 were enrolled in the study. The levels of homocysteine（Hcy）in serum were detected and compared with those of 45 young women without cerebrovascular disease who hospitalized during the same period. The data were analyzed by univariate analysis. The women in stroke group were divided into 3 subgroups according to the area of cerebral infarction, and the differences of serum levels of Hey among the three subgroups were analyzed by one-factor analysis of variance. Results The serum levels of Hcy in stroke group were significantly higher than those in control group（ P 〈 0. 05 ）, however, there were no significant differences in the serum levels of Hcy among the three subgroups（ P 〉 0.05）. Conclusion HHcy is an important risk factor for ischemic stroke in young women, so the detection of s erum levels of Hcy should be regarded as a routine inspection item for young women with acute ischemic stroke.
出处
《河北医药》
CAS
2012年第20期3048-3049,共2页
Hebei Medical Journal
