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奥曲肽联合凝血酶治疗肝硬化合并上消化道出血的疗效观察 被引量:52

奥曲肽联合凝血酶治疗肝硬化合并上消化道出血的疗效观察
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摘要 目的探讨奥曲肽联合凝血酶治疗肝硬化合并上消化道出血的治疗效果。方法选取2004~2012年四川省凉山州第一人民医院消化科收治的96例肝硬化合并上消化道出血患者为研究对象,针对不同治疗方案的疗效进行比较分析。结果 3组患者在实施不同治疗后,两组单独用药与联合治疗组分别比较,联合治疗组在各时间段的止血效果、平均止血时间、总有效率、最短症状改善时间、平均症状改善时间方面均优于另两组,且联合治疗组与另两组组间比较,差异有统计学意义(P<0.05)。结论奥曲肽联合凝血酶治疗肝硬化合并上消化道出血与单一用药相比较,临床治疗效果显著。 Objective To investigate the clinical efficacy for octreotide combined with thrombin in the treatment of cirrhosis with upper gastrointestinal bleeding. Methods 96 cases of cirrhosis with gastrointestinal bleeding from 2004 to 2012 were chosen as the research object. The treatment effect for different treatment options was taken for a comparative analysis. Results After the implementation of the different treatment options, the two groups of drug alone and combined treatment group were compared,the hemostatic effect,the average time to stop bleeding, the total efficiency, the shortest symptom improvement, the average improvement of symptoms timing in the combined treatment group were better than the other two groups. Compared between the combination therapy group and the other two groups, P〈0.05, the difference was with significance. Conclusion Combination of octreotide thrombin cirrhosis and upper gastrointestinal bleeding compared with single drug, the clinical outcomes was significant.
作者 周晓利
出处 《当代医学》 2012年第33期22-24,共3页 Contemporary Medicine
关键词 奥曲肽联合凝血酶 肝硬化合并上消化道出血 临床疗效 Octreotide combined with thrombin Cirrhosis with upper gastrointestinal bleeding Clinical efficacy
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