摘要
目的了解鲍曼不动杆菌的临床分布及其对常用抗生素的耐药情况,为临床抗感染治疗提供依据。方法回顾性分析临床分离的鲍曼不动杆菌的标本来源、感染科室分布及耐药情况。结果从2011年4月～2012年2月临床送检各类标本中共检出鲍曼不动杆菌202株,在临床送检的各类标本中以痰液为主(占所有标本的77.2%);在各科室中,重症监护病房检出率最高(占40.1%);在药敏结果中,鲍曼不动杆菌对亚胺培南耐药率为54.0%、美罗培南为56.5%,对其它抗生素的耐药性均较高。结论鲍曼不动杆菌主要引起呼吸道感染,其对大部分抗菌药物的耐药率较高,目前治疗鲍曼不动杆菌最有效的药物是亚胺培南和美罗培南。为了有效控制感染并减少耐药株的产生,临床应根据药敏试验合理使用抗菌药物。
Objective To investigate the distribution and drug resistance situation of the Acinetobacter baumannii and provide basis for clinical adjustment dose. Methods the origins, distribution infectious offices and drug resistance situations ofAcinetobacter baumannii from April 2011 to February 2012. Results 202 strains ofAcinetobacter baumannii were detected. Among them, sputamentum was main as high as 77.2%, and positive rate of intensive care therapy was the highest which was 40.1%. the results of antimicrobial susceptibility showed the drug resistance rate of imipenem and meropenem were 54.0% and 56.5% respectively. And it was high to other antibiotics. Conclusion Though imipenem and meropenem meropenem are the most effective drugs in Acinetobacter baumannii therapy, drug resistant were the most higher. And the rational use of antimicrobial agents in controlling the infection of Acinetobacter baumannii and reduce the production of resistant strain should accord to the results of drug sensitive test.
出处
《当代医学》
2012年第33期20-22,共3页
Contemporary Medicine
关键词
鲍曼不动杆菌
感染
临床调查
耐药情况
Acinetobacter baumannii
Infection
Clinical investigation
Situation of drug resistence
