摘要
采用反相高效液相色谱法 ,同时测定化妆品中凯松和对羟基苯甲酸甲酯、乙酯、丙酯、丁酯等 5种防腐剂。色谱柱 :10 μm YWG- C18柱 ;流动相 :甲醇 -四氢呋喃 -水 (6 0∶ 5 0∶ 10 0 V/ V) ,紫外检测波长为 2 80 nm,样品用流动相超声提取 ,各组分回收率为 90 .4%～ 10 8.3% ,相对标准偏差为 1.0 %～ 7.5 %。
A method for simultaneous determination of preservatives,such as Kathon and 4 p hydroxybenzoates (methyl p hydroxybenzoate,ethyl p hydroxybenzoate,n propyl p hydroxybenzoate,n buthy p hydroxybenzoate)in cosmetic products was developed successfully It was based on a reversed phase high performance liquid chromatographic separation under the condition of mobile phase using a mixture solution of methanol THF water(60:50:100 V/V)and chromatographic column packed with 10 μ m YWG C 18 ,the UV detection at wave length of 280nm Samples were treated by ultrasonic extraction in mobil phase The recoveries of every component ( n= 6) ranged from 90 4% to 108 3%,and the relative standard deviations ( n= 6) were 1 0% to 7 5%
出处
《环境与健康杂志》
CAS
CSCD
北大核心
2000年第4期238-239,共2页
Journal of Environment and Health
关键词
高效液相色谱法
凯松
对羟基苯甲酸酯
化妆品
High performance liquid chromatography
Kayhon and 4 p hydroxybenzoates
Cosmetics
