摘要
目的:探讨传统巴氏涂片法和液基细胞学法在宫颈癌筛查中的临床意义。方法:分别对12302例和15750例患者分别进行传统巴氏涂片法和液基细胞学检测的宫颈癌筛查。对细胞学阳性者进行阴道镜下活检并分析结果。结果:传统巴氏涂片法和液基细胞学检测的阳性检出率分别为5.45%和6.06%,差异无统计学意义(P>0.05);两种方法与活检符合率分别为22.84%和55.57%,差异有统计学意义(P<0.05);两种方法的假阳性率分别为77.16%和44.42%,差异有统计学意义(P<0.05)。结论:液基细胞学检测用于宫颈癌的筛查与活检的符合率高,假阳性率低,优于传统巴氏涂片,值得在临床推广应用。
Objective： To explore clinical value of traditional Bethesda smears and liquid-based cytology test in the screening of cervical cancer.Methods： Traditional Bethesda smears and liquid-based cytology test were used to screen 12302 and 15750 subjects with cervical cancer,respectively.Biopsy under the colposcope was performed for the subjects with the positive outcome of cytological examination.Results： The positive rates identified by traditional Bethesda smears and liquid-based cytology test were 5.45% and 6.06%,respectively（P0.05）.The coincidence positive rate for traditional Bethesda smear and biopsy under the colposcope was 22.84%.The coincidence positive rate for liquid-based cytology test and biopsy under the colposcope was 55.57%（P0.05）.The fake positive rates for traditional Bethesda smear and liquid-based cytology test were 77.16% and 44.42%,respectively（P0.05）.Conclusion： Liquid-based cytology test is worth to be recommended in the clinical examination of cervical cancer due to its higher coincidence rate with pathological examination and its lower fake-positive rate.
出处
《国际病理科学与临床杂志》
CAS
2012年第5期393-396,共4页
Journal of International Pathology and Clinical Medicine
关键词
宫颈癌筛查
超薄液基细胞学检测
传统巴氏涂片
cervical cancer screening
tinprep cytology test
traditional Bethesda smears
