摘要
目的:研究绿原酸、木犀草苷、3,5-O-双咖啡酰基奎宁酸在杭白菊和贡菊中的稳定性,并预测杭白菊和贡菊的有效期。方法:采用高效液相色谱法测定绿原酸、木犀草苷、3,5-O-双咖啡酰基奎宁酸在杭白菊和贡菊中的含量,在恒温条件下进行加速试验,以获得恒温下的动力参数。根据Arrhenius指数定律预测杭白菊和贡菊在室温下的有效期。结果:在室温条件下杭白菊贮存期为2.25年;贡菊贮存期为4.31年。结论:高温不利于杭白菊和贡菊的稳定,需置于避光阴凉处保存。
Objective： To study the stability of ehlorogenie acid, cynaroside and 3,5-O-discaffeoylquiuc acid in Hangbaiju and Gongju and to predict their term of validity. Method ： Hangbaiju and Gongju were incubated in an environmental chamber at different temperatures and relative humidities. After the incubation, quantitative determination of chlorogenic acid, cynaroside, 3,5-O-discaf- feoylquinc acid in Hangbaiju and Gongju were measured by HPLC. The effective period of the preparation was calculated according to Arrhinius index law. Quantitative determination of 3,5-O-diseaffeoylquinc acid, cynaroside, ehlorogenic acid in Hangju and Gongju were analyzed by HPLC. Result： The stable life of Hangbaiju has been determined as 2.25 years,The stable life of Gongju has been determined as 4. 31 years. Conclusion： The high temperature is not conducive to the stability of Hangbaiju and Gongju, which needs to be placed in a dark and cool place.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2012年第21期3182-3184,共3页
China Journal of Chinese Materia Medica
基金
河南省科技厅重点项目(122102310272)
关键词
杭白菊
贡菊
经典恒温法
有效期
高效液相色谱法
Hangbaiju
Gongju
classic constant temperature accelerated test method
stable life
HPLC
