摘要
目的:研究不同温度下金银花的稳定性,预测其室温下(25℃)的有效期。方法:采用HPLC测定金银花中绿原酸的含量,以初均速法得到其活化能Ea和分解速率常数K,预测有效期。结果:金银花在25℃下有效期为1.29年。结论:用初均速法预测金银花的稳定性,以测定绿原酸含量为指标,其操作简便,结果可靠,所以金银花在储存时应避高温,用室温保存,以保证其质量。
Objective ： To study the content change of chlorogenic acid in honeysuckle under different temperature, and predict its term of validity at room temperature. Method ： The content of chlorogenic acid was assayed by HPLC. The activation energy Ea and the decomposition rate constant K were calculated by initial average rate stability tests and the prediction was carried out. Result： The stable life of honeysuckle has been determined as 1.29 years. Conclusion： The initial average rate stability test was used to predict stable life of honeysuckle, and the results are credible. Higher temperature should be avoided for honeysuckle store, and room temperature should guarantee its quality during storage.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2012年第21期3179-3181,共3页
China Journal of Chinese Materia Medica
基金
河南省科技厅重点项目(122102310272)
关键词
初均速法
金银花
有效期
高效液相色谱法
initial average rate stability tests
honeysuckle
stable life
HPLC
